What is it?
Allergen extract injected into a lymph node rather than under the skin, so the immune cells that drive tolerance meet it directly.
Intralymphatic immunotherapy
Three
injections. Not
three years.
ILIT places allergen directly into a lymph node — three visits across about eight weeks. Find the allergists near you who administer it.
Find a practitionerModels shown. Individual results vary. ILIT is administered off-label in the US — see what to ask your allergist.
Find an ILIT practitioner in your area
Every listing names the supervising allergist, their board certification, and the allergens they treat.
The treatment
Same idea as allergy shots. Different address.
Conventional immunotherapy injects allergen under the skin and relies on repetition to reach the lymph nodes, where the immune system learns tolerance. ILIT goes straight there: a small dose placed into a lymph node in the groin, guided by ultrasound.
3Injections
8 wksStart to finish
30 minPer appointment
No allergen extract is FDA-approved for intralymphatic use. Protocols vary between practitioners; the figures above are typical, not universal.
Totally new to ILIT?
Here is what you should know.
How many appointments?
Three injections, usually four weeks apart, plus an initial consultation. Conventional allergy shots run to roughly a hundred visits.
Does it hurt?
Most people report less discomfort than a skin injection. The needle is fine and the node is shallow, located with ultrasound.
How long does a visit take?
Around thirty minutes, including a short observation period afterwards. The first consultation is longer.
What does it cost?
Practitioners set their own fees, typically $2,000–$4,000 for a full course. Insurance does not cover off-label use.
Who is ILIT for?
Adults and teenagers with confirmed allergy to pollen, dust mite or animal dander who want an alternative to years of shots.
How long does it last?
Follow-up studies report benefit sustained at three years. Longer-term data does not yet exist.
When would I feel a difference?
Many patients notice improvement during the first season after treatment; the full effect builds over the following year.
Allergens treated by listed practitioners
Patient stories
“I had done four years of weekly shots before. Three appointments felt like a rounding error.”
Individual accounts, not outcomes data. Each links to the practitioner who treated the patient.
Find an expert you can trust.
Every listing names a board-certified allergist. We check the certification; the practice supplies the rest.
Find a practitionerFor allergists
Are you a practitioner offering ILIT?
Patients are looking for you. A listing puts your practice on the map, names you as the supervising allergist, and links straight to your own website and phone.
- Free. The Society takes no payment for placement and does not rank listings.
- Verified. We check board certification; you supply the protocol, allergens and hours.
- Yours to keep current. Change your details whenever your practice changes.
Open to board-certified allergists and immunologists administering intralymphatic immunotherapy in the United States.
Important information about ILIT
ILIT is not approved by the FDA for any allergen. Where it is offered in the United States it is administered off-label, at the discretion of the treating physician, using extracts licensed for other routes.
Not everyone is a candidate. Uncontrolled asthma, certain cardiac conditions, pregnancy and some medications rule it out. Only an allergist who has examined you can say.
This directory is an information resource, not medical advice, and a listing is not a recommendation. ILIT Society accepts no payment for placement and does not rank practitioners.
Trials to date have been small. Published follow-up extends to three years; individual results vary. Discuss risks, alternatives and cost with a qualified allergist before starting treatment.