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Allergy shots, tablets or ILIT: how to choose

Three treatments change the immune response instead of masking symptoms. What each one asks of you, and how an allergist weighs them.

Donya Imanirad, MDD. Imanirad, MD··1 min read

Three treatments change the immune response rather than mask symptoms: allergy shots, sublingual tablets or drops, and ILIT. They treat the same allergies. They ask very different things of you.

Allergy shots

Weekly injections for months, then monthly for three to five years, each with a wait afterwards. The best long-term evidence, and usually covered by insurance. The cost is time.

Tablets and drops

Taken daily at home for three years, for a handful of allergens with approved products. No needles and no visits, but the discipline of a daily dose and a narrower range of allergens.

ILIT

Three injections over about two months, under ultrasound, then done. The shortest course and the youngest evidence, off-label and usually self-pay. For people who cannot commit to years of visits, it is often the only realistic option.

Choosing

Ask the allergist which of the three they would choose for your allergens, your calendar and your budget, and why. A practice that offers all three has no reason to steer you.

Published 21 August 2026

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